Nootkatone

Nootkatone

Use against biting and nuisance pests

Nootkatone is a citrus ingredient that is characteristically associated with grapefruit that has the potential to become an effective repellent against a range of insect pests including ticks, bed bugs and mosquitoes.

For example, the US Centers for Disease Control (CDC) has demonstrated that nootkatone is a highly effective agent against the ticks that transmit Lyme disease.

Still from movie. Ingredient nootkatone can protect you against, mosquito, bed bug, lice, fire ant, dust mite.

To view raw video footage of an untreated finger exposed to ticks vs a finger treated with nootkatone, please click here.

However, prior to initiating sales of insect control products that utilise nootkatone as an active ingredient, it will be necessary to obtain regulatory approval from the US Environmental Protection Agency (EPA) and similar governing bodies in other countries.

Progress in recent years

In 2015 the EPA has already ruled that nootkatone meets the standards for a bio-pesticide classification. This classification allows for a potentially expedited registration process. We are making good progress in this process, and given this continues, we expect approval in 2018. We are also working on regulatory approval of nootkatone in a number of other geographies.

In 2016 we signed an agreement with the CDC, which grants Evolva the exclusive worldwide patent rights to develop and commercialise nootkatone for the control of a wide range of disease and virus vectors such as ticks, mosquitoes, fleas, flies, lice, bed bugs, and other biting insects. In 2016 we also announced that the US National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), is sponsoring studies to test Evolva’s nootkatone against mosquitoes infected with Zika virus. The study focus is nootkatone in multiple formulations against wild type and insecticide-resistant mosquitoes that carry the virus.

During 2016 we worked with multiple potential customers, as well as on our own behalf, in demonstrating the utility of nootkatone against a wide range of insects and related pests. Part of this work involves the design of new repellent formulation against mosquitos, ticks and bed bugs.

Looking for a visual explanation of nootkatone? Find above our short animated video on nootkatone.

  • CSU tests NK against Zika-infected skeeters

    TV news covers Evolva's nootkatone progress

    CBS Denver
  • Lyme Disease: Inside America’s Mysterious Epidemic

    Lyme has forced its way into cultural and medical relevance

    Rolling Stone
  • Ergot alkaloids made in yeast

    We like to say that yeast is the microbial cell factory of the future. This paper expands on that idea, focusing on ergot alkaloid.

    Microbial Cell Factories
More articles
cancel
  • Topped our upper estimate! Evolva raises CHF 86M ($86M). Cash position now > CHF 100M ($100M). https://t.co/aiPI46jsTK

Sign up to receive our
Press Releases!

Sign up