Resveratrol: A matter of healthy ageing

Resveratrol is a polyphenol found in plants, peanuts, grapes, and berries to name a few. There is a significant and growing body of evidence that has shown that resveratrol can produce a positive impact on the systems that decline with age like heart, bone, and brain. Scientists have also found evidence that resveratrol can mimic the effects of a calorie-restricted diet. To date, some 9,000 studies have been published on resveratrol.

Learn more about resveratrol from our movie:

Still from the animated resveratrol movie visualizing that Resveratrol can have a positive impact on various healthy ageing variables. Like bone health, blood glucose, insulin and blood pressure levels.

Still from the animated resveratrol movie visualizing that Resveratrol can have a positive impact on various healthy ageing variables. Like bone health, blood glucose, insulin and blood pressure levels.

Evolva’s resveratrol is the only resveratrol produced entirely by fermentation using yeast. It is made using natural and sustainable feedstocks and has a stable, traceable and reliable supply chain. Evolva’s resveratrol marks a major step forward for the category, which has been dominated by resveratrol sourced from China from the extract of an invasive and environmentally destructive weed. Our closed-system fermentation process avoids the possibility of environmental contaminants, such as Emodin and PAHs, and provides the desired consistency and purity (>98%) through a brewing process.

9,000 studies and counting

Resveratrol has been widely studied, with some 9,000 papers published to date. The NCBI library  provides access to many of these papers, click here to go there. Whilst resveratrol is perhaps most famous for driving significant extensions in life-span in animals, such effects have never been shown in humans. However, many studies in humans have shown positive effects on age-related health indications.

A thorough review of the literature on resveratrol’s effects was published by Novelle et al. in January 2015.

Evolva’s resveratrol has Self-Affirmed GRAS status in the United States and Novel Foods Approval for use in Dietary Supplements and Food for Special Uses in the EU.

Market Potential

A 2012 report by Frost & Sullivan estimated resveratrol sales at some USD 50 million, with over 80% being used in the US dietary supplement market. Smaller amounts are used in other countries and in cosmetics.

We believe that the advent of a high quality, affordable resveratrol has the potential to significantly expand the use of resveratrol worldwide, allowing use outside the dietary supplement market in areas such as animal health, oral care, medical nutrition, and pharmaceuticals. What this translates to in actual market potential is, as always with innovative new products, hard to estimate.

Progress in Recent Years

We launched resveratrol in late 2014, the production volumes and sales were very limited but the market feedback was very positive. As of mid-2016 the production process improved, partly due to the introduction of yeast strains with roughly twice the production efficiency as at launch. Ready for sale we established our B2B online shop and launched in early 2017 the Veri-te resveratrol brand for healthy ageing opening up new opportunities for jointly branded finished products.

In addition to resveratrol’s use in dietary supplements for bone health, blood glucose control, cognition, cardiovascular health, and women’s health, we are exploring a number of other commercial applications like oral care, cosmetics, personal care, pharmaceuticals and animal nutrition.

  • Resveratrol increases bone mineral density in obese men

    This study looked at resveratrol's impact on bone health in overweight men.

    J Clin Endcrn & Metab
  • Resveratrol impacts Alzheimer’s Disease Biomarker

    Randomised, placebo-controlled, double-blind trial examined resveratrol's effects on Alzheimer's disease.

    Neurology
  • Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition

    Resveratrol's remarkable role in autophagy

    Scientific Reports
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